Biochemistry of platelets (II): Platelet receptors.

The Biochemistry Questions Site


Platelet aggregates


Platelet membrane is rich in glycoproteins organized as receptors of very different types: tyrosine kinase receptors, integrin family receptors, receptors rich in Leucine (LRR), protein G linked transmembrane receptors, immunoglobulin super family proteins, lectins and others.


Many of these receptors play an important role in the haemostatic function of platelets, participating in the interaction among platelets, between platelets and vascular tissue, and among platelets and coagulation factors and other agonists (ADP, epinephrine, thromboxane A2, and others)


Other platelet membrane receptors are involved in the participation of platelets in processes such as inflammation, tumor growth, metastasis and immunologic type reactions.


From the medical point of view, GPIIb-IIIa and GPIb receptors are particularly important.


[GP] IIb-IIIa is the most abundant receptor in the platelet surface, representing almost 15 % of all the proteins in the cell surface. This receptor is a member of the Integrin receptors…

View original post 313 more words


Author: Tarono's

I'm, a freelance writer, Virtual Assistant, does data entry, article writing transcription etc.

Leave a Reply

Please log in using one of these methods to post your comment: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s